If not treated effectively, corneal infections can result in serious complications, such as corneal ulcers or corneal melting, which can lead to vision loss.
Treatment of corneal infections generally includes the use of a combination of antibiotics and/or antiviral and/or antifungal eye drops. However, a number of factors still limit the efficacy of standard therapies, primarily including the antimicrobial resistance.
Antimicrobial resistance is the natural ability of bacteria to survive and multiply even in the presence of antimicrobials. Corneal infections caused by antimicrobial-resistant bacteria are more challenging to treat and have a high probability of therapeutic inefficacy and risk of vision loss.
There is high demand for solving the need of more effective therapies for corneal infections without increasing the risk of antimicrobial resistance.